CELLULAR
Research Products

Provia currently offers researchers access to mesenchymal stem cells from dental pulp (DPSC) found in human:
 

• third molars

• exfoliated teeth

• follicular tissue

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Provia is preparing to launch additional products that include stem cells from:
 

• cord blood

• adipose tissue

• placental tissue

• amniotic fluid

• synovial fluid

DENTAL PULP
(DSPC)

Provia currently offers researchers access to mesenchymal stem cells from dental pulp (DPSC) found in human:
 

• third molars

• exfoliated teeth

• follicular tissue

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MSCs from Dental Pulp (DPSC) are a significant source of stem cells that are known to express important transcription factors such as:

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• oct4

• sox2

• klf4

• nanog

• c-myc – an indicator of their pluripotency. 

Flow cytometric analysis shows that these cells are positive for:

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• CD73

• CD90

• CD105

Flow cytometric analysis shows that these cells are negative for:

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• CD34 and CD45 – suggesting mesenchymal stem cells. 

Under appropriate culture conditions, DPSCs have been shown to differentiate into the following types of cells:

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• osteogenic

• adipogenic

• neurogenic cells. 

Certain sources of DPSC show considerable proliferative capacity, like those found in Exfoliated Deciduous Teeth (SHED).